Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Unified Medical Language System® (UMLS®)

New and Updated Sources (Expanded Representation Information) - 2025AA Release
What's New for 2025AA
 
General Information:  
 
For 2025AA, there is 1 new translation source (MDRISL_27_1) and 81 updated sources (including translation sources and subsources).  
 
MDRISL is the Icelandic Edition of the Medical Dictionary for Regulatory Activities Terminology (MedDRA).
 
For detailed information about sources that are new or have had changes made (e.g., new term types, new attribute names, etc.):
 
Healthcare Common Procedure Coding System, HCPCS2025_04
LOINC, LNC280
Medical Dictionary for Regulatory Activities Terminology (MedDRA), MDR27_1
Medical Dictionary for Regulatory Activities Terminology (MedDRA), Icelandic Edition, MDRISL27_1
MEDCIN, MEDCIN3_2024_12_20
NCI Thesaurus, NCI2024_10D
RXNORM Vocabulary, RXNORM_20AA_250303F
------------------------------------------
 
Source: Healthcare Common Procedure Coding System 
VSAB: HCPCS2025_04 
 
This version includes HCPT2025_04, the HCPCS Version of Current Procedural Terminology (CPT).
 
 
Discussion:
 
HCDT has not been updated due to licensing issues.
------------------------------------------
 
Source: LOINC
VSAB: LNC280
 
1. New abbreviation| Expansion:
ElecCon|Electrical Conductivity (Property)
XR.3D|X-ray 3 dimensional (Method)
 
2. New class| Description:
PANEL.SURVEY.WHYMP|West Haven-Yale Multidimensional Pain Inventory
PANEL.CLIN.VET|Clin Vet Panel
-------------------------------------------------------
 
Source: Medical Dictionary for Regulatory Activities Terminology (MedDRA)
VSAB: MDR27_1
 
Dropped relationship | relationship attribute (RELA) | RELA inverse:
SY|mth_british_form_of|mth_has_british_form
 
 
Discussion:
As of this release, the UMLS will no longer create atoms for the 
American spellings of MDR. MDR data includes British spellings with its 
American spelling counterpart included at the LLT level.  
 
The relationship attribute (RELA) "mth_british_form_of/mth_has_british_form" has been deprecated.
 
Expanded versions of strings with identified abbreviations will continue 
to be made.
-------------------------------------------------------
 
Source: Medical Dictionary for Regulatory Activities Terminology (MedDRA), Icelandic Edition
VSAB: MDRISL27_1
 
1. New termtype (TTY) | Description
    AB|Abbreviation
    HG|High Level Group Term
    HT|Hierarchical term
    LLT|Lower Level Term
    OL|Non-current Lower Level Term
    OS|System-organ class
    PT|Designated preferred name
    SMQ|Standardised MedDRA Query 
 
2. New relationship | relationship attribute (RELA) | RELA inverse:
    RQ|classifies|classified_as
    RO|has_member|member_of
    RO|member_of|has_member
    RO|translation_of|has_translation
    SY|expanded_form_of|has_expanded_form
    SY|translation_of|has_translation
 
3.  New attribute name (ATN) | Description:
    MISO|MedDRA Serial Code International SOC Sort Order Digit (01-26)
    MPS|MedDRA primary SOC (PTs may have multiple treepositions, but each has a primary soc)
    SMQ_ALGO|Standardised MedDRA Query (SMQ) Algorithm. Boolean expression of algorithm for the SMQ. "N" if the SMQ does not utilize an algorithm.
    SMQ_LEVEL|Standardised MedDRA Query (SMQ) Level. Value between 1 and 5 identifying the level of the SMQ within the hierarchy of SMQs; 1 is the most general, 5 is the most narrow.
    SMQ_SOURCE|Standardised MedDRA Query (SMQ) Source. Source for the development of the SMQ, e.g. medical references.
    SMQ_STATUS|Standardised MedDRA Query (SMQ) Status. "A" = active; "I" = inactive.
    SMQ_TERM_ADDVERSION|Standardised MedDRA Query (SMQ) Addition Version. Version of MedDRA in which term was added to the SMQ.
    SMQ_TERM_CAT|Standardised MedDRA Query (SMQ) Term Category. A single alphabetical letter indicating the category of the term for application of the SMQ algorithm. If the SMQ does not use algorithms, then all Term_category values are assigned "A." For a child SMQ, this field is assigned "S."
    SMQ_TERM_LEVEL|Standardised MedDRA Query (SMQ) Level. Value between 1 and 5 identifying the level of the SMQ within the hierarchy of SMQs; 1 is the most general, 5 is the most narrow.
    SMQ_TERM_LMVERSION|Standardised MedDRA Query (SMQ) Last Modified Version. Version of MedDRA in which term was last modified in the SMQ.
    SMQ_TERM_SCOPE|expanded_form|Standardised MedDRA Query (SMQ) Term Scope. Defines the MedDRA term as a member of the broad scope (1), narrow scope (2) of the SMQ search, or a child SMQ (0) (zero).
    SMQ_TERM_STATUS|Standardised MedDRA Query (SMQ) Term Status. Identifies a term as active ("A") or inactive ("I") within this SMQ.
    SMQ_TERM_WEIGHT|Standardised MedDRA Query (SMQ) Term Weight. Used for some SMQ algorithms; "0" is used as default.
    SOS|Scope Statement
 
 
Discussion:
 
New translation source.
------------------------------------------
 
Source: MEDCIN
VSAB: MEDCIN3_2024_12_20
 
Dropped relationship | relationship attribute (RELA) | RELA inverse:
RO|has_definitional_manifestation|definitional_manifestation_of
-------------------------------------------------------
 
Source: NCI Thesaurus
VSAB: NCI2024_10D
 
New relationship | relationship attribute (RELA) | RELA inverse:
RO|has_pro-ctcae_attribute|is_pro-ctcae_attribute_of
RO|has_ped-pro-ctcae_attribute|is_ped-pro-ctcae_attribute_of
RO|has_pro-ctcae_attribute_value|is_pro-ctcae_attribute_value_of
RO|has_ped-pro-ctcae_attribute_value|is_ped-pro-ctcae_attribute_value_of
RO|has_pro-ctcae_parent|is_pro-ctcae_parent_of
RO|has_ped-pro-ctcae_parent|is_ped-pro-ctcae_parent_of
------------------------------------------
 
Source: RXNORM Vocabulary
VSAB: RXNORM_20AA_250303F
 
This version includes:
    ATC_2025_02_10 (Anatomical Therapeutic Chemical Classification System)
    CVX_2024_12_18_25_03_03 (Vaccines Administered)
    DRUGBANK5.0_2025_02_06 (DrugBank)
    GS_2025_02_07 (Gold Standard Drug Database)
    MMSL_2025_02_01 (Multum MediSource Lexicon)
    MMX_2025_02_07 (Micromedex RED BOOK)
    MTHCMSFRF_2020_25_03_03 (Metathesaurus CMS Formulary Reference File)
    MTHSPL_2025_02_22 (Metathesaurus FDA Structured Product Labels)
    NDDF_2025_02_05 (FDB MedKnowledge)
    USP_2025_01_30 (USP Compendial Nomenclature)
    VANDF_2025_01_31 (Veterans Health Administration National Drug File)
 
 
Dropped attribute name (ATN):
DIETARY_SUPPLEMENT
-----------------------------------------------
 

Last Reviewed: May 5, 2025